Type II Diabetes Mellitus And Anti-Diabetic Therapy Patterns In Hospital X, Central Java
DOI:
https://doi.org/10.58471/health.v2i02.121Keywords:
theraphy pattern, diabete mellitus, T2DMAbstract
Type 2 DM can be a risk factor for arteriosclerotic cardiovascular disease complications (coronary heart disease, stroke, and peripheral arterial disease), heart failure, chronic renal failure, and cardiovascular risk. This cross-sectional study was conducted on 100 type 2 diabetic patients who were prescribed anti-diabetic therapy. The prescription pattern was analyzed and adherence to treatment guidelines was done by comparing with the 2021 PERKENI guidelines. The results of the distribution of the characteristics of T2DM respondents at X Hospital 2022 were mostly aged> 45 years as much as 87%, the most gender was male as much as 54%, the most comorbidities were 97% of respondents, the most treatment pattern was monotherapy as much as 64%, the highest number of drugs received by patients was 81% with criteria> 5 drugs.
References
American Diabetes Association. (2022). Standards of Medical Care in Diabetes - Abridged for Primary Care Providers. Clinical Diabetes, 40(1), 10–38. https://doi.org/10.2337/cd22-as01
Annani-Akollor, M. E., Addai-Mensah, O., Fondjo, L. A., Sallah, L., Owiredu, E.-W., Acheampong, E., & Akamugri, S. (2019). Predominant Complications of Type 2 Diabetes in Kumasi: A 4-Year Retrospective Cross-Sectional Study at a Teaching Hospital in Ghana. Medicina, 55(5), 125. https://doi.org/10.3390/medicina55050125
Ashwell, S. G., Bradley, C., Stephens, J. W., Witthaus, E., & Home, P. D. (2008). Treatment Satisfaction and Quality of Life With Insulin Glargine Plus Insulin Lispro Compared With NPH Insulin Plus Unmodified Human Insulin in Individuals With Type 1 Diabetes. Diabetes Care, 31(6), 1112–1117. https://doi.org/10.2337/dc07-1183
Brunetti, P., Muggeo, M., Cattin, L., Arcangeli, A., Pozzilli, P., Provenzano, V., Francesconi, A., Calatola, P., & Santeusanio, F. (2010). Incidence of severe nocturnal hypoglycemia in patients with type 1 diabetes treated with insulin lispro or regular human insulin in addition to basal insulin glargine. Nutrition, Metabolism and Cardiovascular Diseases, 20(7), 519–526. https://doi.org/10.1016/j.numecd.2009.05.007
Camire, E., Moyen, E., & Stelfox, H. T. (2009). Medication errors in critical care: risk factors, prevention and disclosure. Canadian Medical Association Journal, 180(9), 936–943. https://doi.org/10.1503/cmaj.080869
Candido, R., Wyne, K., & Romoli, E. (2018). A Review of Basal-Bolus Therapy Using Insulin Glargine and Insulin Lispro in the Management of Diabetes Mellitus. Diabetes Therapy, 9(3), 927–949. https://doi.org/10.1007/s13300-018-0422-4
Chaudhury, A., Duvoor, C., Reddy Dendi, V. S., Kraleti, S., Chada, A., Ravilla, R., Marco, A., Shekhawat, N. S., Montales, M. T., Kuriakose, K., Sasapu, A., Beebe, A., Patil, N., Musham, C. K., Lohani, G. P., & Mirza, W. (2017). Clinical Review of Antidiabetic Drugs: Implications for Type 2 Diabetes Mellitus Management. Frontiers in Endocrinology, 8. https://doi.org/10.3389/fendo.2017.00006
Chen, M., Wang, Y., Feng, P., Liang, Y., Liu, Q., Yang, M., Lu, C., Shi, P., Cheng, J., Ji, A., & Zheng, Q. (2023). Association between Age at Type 2 Diabetes Onset and Diabetic Retinopathy: A Double-Center Retrospective Study. Journal of Diabetes Research, 2023. https://doi.org/10.1155/2023/5919468
Chiang, L., Huang, Y., & Tsai, T. (2021). Clinical pharmacy interventions in intensive care unit patients. Journal of Clinical Pharmacy and Therapeutics, 46(1), 128–133. https://doi.org/10.1111/jcpt.13265
de Souza, K. Irfan, F. Masud, & M.W. Saif. (2016). Diabetes Type 2 and Pancreatic Cancer: A History Unfolding. JOP, 144–148.
Diabetes. (2020). Corticosteroids are used to reduce harmful inflammation but can lead to diabetes - often referred to as steroid diabetes. https://www.diabetes.co.uk/drug-induced-diabetes.html
Endokrinologi Indonesia PEDOMAN PENGELOLAAN DAN PENCEGAHAN DIABETES MELITUS TIPE, P. (n.d.). PEDOMAN PENGELOLAAN DAN PENCEGAHAN DIABETES MELITUS TIPE 2 DEWASA DI INDONESIA-2021 PERKENI i Penerbit PB. PERKENI.
Ewald, N. (2013). Diagnosis and treatment of diabetes mellitus in chronic pancreatitis. World Journal of Gastroenterology, 19(42), 7276. https://doi.org/10.3748/wjg.v19.i42.7276
Fogelman, Y., Kitai, E., Blumberg, G., Golan-Cohen, A., Rapoport, M., & Carmeli, E. (2017). Vitamin B12 screening in metformin-treated diabetics in primary care: were elderly patients less likely to be tested? Aging Clinical and Experimental Research, 29(2), 135–139. https://doi.org/10.1007/s40520-016-0546-1
Fulcher, G. R., Gilbert, R. E., & Yue, D. K. (2005). Glargine is superior to neutral protamine Hagedorn for improving glycated haemoglobin and fasting blood glucose levels during intensive insulin therapy. Internal Medicine Journal, 35(9), 536–542. https://doi.org/10.1111/j.1445-5994.2005.00902.x
Fullerton, B., Siebenhofer, A., Jeitler, K., Horvath, K., Semlitsch, T., Berghold, A., & Gerlach, F. M. (2018). Short-acting insulin analogues versus regular human insulin for adult, non-pregnant persons with type 2 diabetes mellitus. Cochrane Database of Systematic Reviews. https://doi.org/10.1002/14651858.CD013228
Herdaningsih, S., Muhtadi, A., Lestari, K., & Annisa, N. (2016). Potential of Drug-Drug Interaction in Polypharmacy Prescription: Retrospective Study on a Drugstore in Bandung. Indonesian Journal of Clinical Pharmacy, 5(4), 288–292. https://doi.org/10.15416/ijcp.2016.5.4.288
International Diabetes Federation (IDF) 9th Atlas. (2019). International Diabetes Federation. https://diabetesatlas.org/atlas/ninth-edition/
International Diabetes Federation. (2021). IDF Diabetes Atlas, 10th edn.
International Diabetes Federation. (2022). IDF Diabetes Atlas 2022 Reports. IDF Diabetes Atlas 2022 Reports. https://diabetesatlas.org/2022-reports/
Kalra, S., Kalra, B., Agrawal, N., & Unnikrishnan, A. (2011). Understanding diabetes in patients with HIV/AIDS. Diabetology & Metabolic Syndrome, 3(1), 2. https://doi.org/10.1186/1758-5996-3-2
Khunti, K., Giorgino, F., Berard, L., Mauricio, D., & Harris, S. B. (2020). The importance of the initial period of basal insulin titration in people with diabetes. Diabetes, Obesity and Metabolism, 22(5), 722–733. https://doi.org/10.1111/dom.13946
Lipska, K. J., Krumholz, H., Soones, T., & Lee, S. J. (2016). Polypharmacy in the Aging Patient. JAMA, 315(10), 1034. https://doi.org/10.1001/jama.2016.0299
Marathe, P. H., Gao, H. X., & Close, K. L. (2017). American Diabetes Association Standards of Medical Care in Diabetes 2017. Journal of Diabetes, 9(4), 320–324. https://doi.org/10.1111/1753-0407.12524
Melo, K. F. S., Bahia, L. R., Pasinato, B., Porfirio, G. J. M., Martimbianco, A. L., Riera, R., Calliari, L. E. P., Minicucci, W. J., Turatti, L. A. A., Pedrosa, H. C., & Schaan, B. D. (2019). Short-acting insulin analogues versus regular human insulin on postprandial glucose and hypoglycemia in type 1 diabetes mellitus: a systematic review and meta-analysis. Diabetology & Metabolic Syndrome, 11(1), 2. https://doi.org/10.1186/s13098-018-0397-3
Noale, M., Veronese, N., Cavallo Perin, P., Pilotto, A., Tiengo, A., Crepaldi, G., & Maggi, S. (2016). Polypharmacy in elderly patients with type 2 diabetes receiving oral antidiabetic treatment. Acta Diabetologica, 53(2), 323–330. https://doi.org/10.1007/s00592-015-0790-4
Padhi, S., Nayak, A. K., & Behera, A. (2020). Type II diabetes mellitus: a review on recent drug based therapeutics. In Biomedicine and Pharmacotherapy (Vol. 131). Elsevier Masson SAS. https://doi.org/10.1016/j.biopha.2020.110708
PERKENI. (2015). Konsensus Pegendalian dan Pencegahan Diabetes mellitus Tipe 2 di Indonesia . PERKENI.
S.E. Kahn, M.E. Cooper, & S.D. Prato. (2014). Pathophysiology and Treatment of Type 2 Diabetes: Perspectives on the Past, Present and Future. Lancet , 383, 1068–1083.
Soeatmadji, D. W., Rosandi, R., Saraswati, M. R., Sibarani, R. P., & Tarigan, W. O. (2023). Clinicodemographic Profile and Outcomes of Type 2 Diabetes Mellitus in the Indonesian Cohort of DISCOVER: A 3-Year Prospective Cohort Study. Journal of the ASEAN Federation of Endocrine Societies, 38(1), 68–74. https://doi.org/10.15605/jafes.038.01.10
Versita, R., Handayani, D., & Adiningsih, R. (2022). Relationship Patterns Of Medicine Use On The Long Of Treatment In Diabetes Mellitus Patient. In Medical Sains : Jurnal Ilmiah Kefarmasian (Vol. 7, Issue 4).
Zhao, Q., Li, H., Ni, Q., Dai, Y., Zheng, Q., Wang, Y., Ke, T., Li, L., Zhao, D., Dong, Q., Ji, B., Shi, J., Peng, Y., Zhang, Y., Xu, F., & Wang, W. (2022). Follow‐up frequency and clinical outcomes in patients with type 2 diabetes: A prospective analysis based on multicenter real‐world data. Journal of Diabetes, 14(5), 306–314. https://doi.org/10.1111/1753-0407.13271
